Nearly 20,000 men over 40 years of age, were followed up for a 12 year period and were found to have a lower risk of major cardiovascular disease if they took multivitamin supplements for 20 or more years. Dietary sources of vitamins should always be our first priority.
Rautiainen S, Rist PM, Glynn RJ, Buring JE, Gaziano JM, Sesso HD.
Multivitamin Use and the Risk of Cardiovascular Disease in Men. J Nutr. 2016 Jun;146(6):1235-40. doi: 10.3945/jn.115.227884. Epub 2016 Apr 27. https://www.ncbi.nlm.nih.gov/pubmed/27121531