Curcumin extract alone or combined with saffron may help depression and anxiety, as well as being useful as an anti-inflammatory for joint pains.
Adrian L. Lopresti , Peter D. Drummond. Efficacy of curcumin, and a saffron/curcumin combination for the treatment of major depression: A randomised, double-blind, placebo-controlled study. Journal of Affective Disorders Volume 207, 1 January 2017, Pages 188–196 http://www.sciencedirect.com/science/article/pii/S0165032716310217